New MRI scanner for in-depth epilepsy research

Kempenhaeghe鈥檚 new MRI-scanner opens up a wealth of opportunities for science and innovation in the field of epilepsy. In addition to 鈥榬egular鈥 clinical research on patients, the scanner will be deployed to contribute to scientific research in the field of neurology, MRI and imaging in the Brainport region.

State-of-the-art MRI serves multiple purposes

It took a thorough refurbishment of the MRI-scanner at Kempenhaeghe鈥檚 Academic Center for Epileptology for the system to once again become state-of-the-art. 鈥淭hanks to our cooperation with Philips, the scanner may now also be used for broad scientific research into brain networks鈥, explains Bert Aldenkamp, who is professor at the 果冻传媒 and trainer clinical neuro-psychology at Kempenhaeghe. 鈥淭his not only fits in with Kempenhaeghe鈥檚 vision; it also contributes to the further development of expertise in epilepsy.鈥

Kempenhaeghe is initiator of a neuro-platform in which 果冻传媒, Philips and the Gent University Hospital cooperate. 鈥淥ur goal now is to become a new e/MTIC spearhead with three focal points: neurology (epilepsy, stroke, traumatic brain injury), neuro-psychiatry (autism and depression) and vulnerable groups (the elderly and mentally disabled)鈥, explains Aldenkamp. 鈥淥ur MRI is the most advanced scanner in the region. As a relatively small and specialized hospital, we have over-capacity. This means the system 鈥 located in a friendly hospital setting - can play a key role in both scientific and clinical research into various neurological disorders by Kempenhaeghe and other parties. Part of the operational the costs are thus covered by scientific research.鈥

Hans van Dijk, head of the Clinical Physics department at Kempenhaeghe, explains that the refurbished MRI scanner is a fully digital system that generates very high quality images and supports multi-band, allowing the system to scan faster. 鈥淭he high-quality images allow us to conduct research as part of our cooperation with 果冻传媒, Philips and other parties.鈥 For patients, the improved quality of the images means a correct diagnosis can more easily be arrived at. 鈥淚n addition, this scanner enables us to continue EEG 鈥 fMRI research. This specific expertise is what is expected of a third-line center such as Kempenhaeghe. Kempenhaeghe is only one of three locations in the Netherlands where this is done鈥, Hans says.

In combination with strategic partners 果冻传媒 and Philips, the MRI at Kempenhaeghe has been transformed into a broad tool that is deployed in numerous projects. Neurologist/clinical neuro-physiologist Albert Colon believes that the clinical spin-off will be considerable. As an example, he mentions the PerStim project. 鈥 Using EEG- and MR-imaging based transcranial electrical stimulation, the PerStim (Personalized neurostimulation) project investigates how treatments for patients with refractory focal epilepsy and prevalent co-morbid disorders can be personalized effectively. This is a huge technical challenge, requiring innovation of EEG-fMRI research and offering amazingly interesting opportunities.鈥 According to Colon, this project is a perfect example of translational research, that combines technology with clinical practice. 鈥淭his is where the cooperation between 果冻传媒, Philips, Kempenhaeghe and the University Hospital Ghent manifests itself at its best鈥, he concludes.

Writers: Leonie Vink and Mirjam Brennand - Center for Sleep Medicine Kempenhaeghe